Global Label-Free Array SystemsMarket Regional Analysis
North America is expected to holddominant position in the global Label-FreeArray Systems Market over the forecast period, owing to the wide spreadpresence of the key manufacturers in the North American. For instance, GeneralElectric, Reichert, Inc., NanoSPR Devices, Bruker Corporation, and others aresome of the key manufacturers, which have their presence in the North Americaregion.
Moreover, many acquisitions havetaken place in the recent past in the global label-free array systems marketfor the development and introduction of new products. For instance, in 2018,Bruker Corporation acquired Sierra Sensors GmbH, a manufacturer of innovativeanalytical biosensors-based on SPR detection. Sierra Sensors GmbH have thetechnology to measure the specificity, affinity, thermodynamics and kineticrates of interaction between molecules, while Bruker Corporation have thefacilities for mass spectrometry, nuclear magnetic resonance (NMR) and X-raycrystallography. Both the technologies can be combined efficiently for thedevelopment in drug discovery process. The above factors are expected to boostthe global label-free array systems market growth over the forecast period.
Label-free array systems tools havemany applications such as drug development, diagnostics etc. Label-free arraysystems comprises two types of biosensors such as optical biosensors andimpedance-based biosensors, which involves techniques such as surface plasmonresonance (SPR), isothermal titration calorimetry (ITC), bio-layerinterferometry, and others. Moreover, SPR is the most commonly used technique.Many key players manufacture modified versions of SPR, which are marketed alongwith the SPR accessories and consumables. For instance, General ElectricHealthcare, manufactures Biacore T200, a versatile instrument for high qualitycharacterization of molecular interactions, where interactions from ions toviruses can be evaluated.
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Moreover, General Electric alsomanufactures and markets SPR consumables such as sensor chip, running buffers,regeneration solution, capture reagents, and others. Some other manufacturersoperating in the global label-free array systems market include General Electric,BioNavis Ltd, and others.
Global Label-Free Array SystemsMarket Drivers
Increasing adoption of label-freearray systems in the drug discovery process is expected to drive the globallabel-free array systems market growth over the forecast period. For instance,according to the National center for Biotechnology Information, (NCBI), 2016,label-free array systems are extensively used for secondary screening to findthe lead molecule for the drug development process from the small molecule hitsand it is also used for lead optimization to find the candidate drug from theleads molecules. Moreover, according to the same source, currently thelabel-free array systems are extensively used for evaluating kinetics betweenthe drug molecule and its receptor, as it is most important bond that is characterizedfor drug discovery process.
Leading manufacturers are focusedon manufacturing new products in the global label-free array systems marketover the forecast period. For instance, in 2018, Bruker Corporation launched amodified version of SPR, Sierra SPR-32 system, with higher sensitivity,modified instrument control software to enable highest SPR throughput withoutstanding sensitivity. These factors are expected to drive the globallabel-free array systems market growth over the forecast period.
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Global Label-Free Array SystemsMarket Restraints
Lack of skilled persons toperform label-free techniques in developed as well as in the emerging economiesis expected to hamper growth of the global label-free array systems market overthe forecast period. The protocols used in the techniques are very specific andrequires a trained person to carry out the procedure. The procedure should becarried out with higher precision and less errors.
Moreover, SPR products are veryexpensive and this is expected to hinder the growth the market. For instance,cost of imaging systems offered by Biacore (acquired by GE Healthcare) rangebetween US$ 200,000 and US$ 300,000. Moreover, reagents supporting such systemsare very costly, which increases the overall cost per interaction. Thesefactors are expected to restrain the global label-free array systems market growthover the forecast period.
Global Label-Free Array SystemsMarket Key Players
Some of the key manufacturersoperating in the global label-free array systems market include GeneralElectric Healthcare, BioNavis Ltd, Reichert, Inc., Metrohm India Limited,Horiba instruments Incorporated, ABL&E Group, plasmetrix.com, Nicoya,NanoSPR Devices, Biosensing Instrument, and Bruker Corporation.
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