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The opening research assessing Low Dose Naltrexone as an adjunct therapy in fibromyalgia was a single-blind, placebo-crossover study and included ten women undergoing the condition. After the initial couple weeks of placebo, LDN was given for eight weeks in a 4.5 mg dose with a subsequent two-week washout phase.
Clinical significance of Low Dose Naltrexone in treating Fibromyalgia and Complex Regional Pain Syndrome
The opening research assessing Low Dose Naltrexone as an adjunct therapy in fibromyalgia was a single-blind, placebo-crossover study and included ten women undergoing the condition. After the initial couple weeks of placebo, LDN was given for eight weeks in a 4.5 mg dose with a subsequent two-week washout phase.